Title:
グリオキサラーゼIII活性を有するポリペプチド、それをコードするポリヌクレオチドおよびその使用
Document Type and Number:
Japanese Patent JP2011515083
Kind Code:
A
Abstract:
The present invention relates to a novel polypeptide having the enzymatic activity of conversion of methylglyoxal to lactic acid in a single step (known as glyoxalase III activity), a polynucleotide having a nucleotide sequence encoding such polypeptide and uses thereof. The invention relates to the modulation of the glyoxalase III activity in a microorganism by varying the expression level of the polynucleotide coding for such polypeptide. The invention also relates to the production of commodity chemicals, especially 1,2-propanediol, acetol, and lactic acid by fermenting microorganisms wherein their glyoxalase III activity is modulated.
Inventors:
Francois, Felke
Philip and Scaille
Philip and Scaille
Application Number:
JP2011500181A
Publication Date:
May 19, 2011
Filing Date:
March 16, 2009
Export Citation:
Assignee:
Metabolic explorer
International Classes:
C12N15/09; C12N1/14; C12N1/15; C12N1/16; C12N1/19; C12N1/20; C12N1/21; C12N9/00; C12P7/18; C12P7/26; C12P7/56
Attorney, Agent or Firm:
Hirohito Katsunuma
Yukitaka Nakamura
Noritaka Yokota
Takeyasu Ito
Omori Miko
Yukitaka Nakamura
Noritaka Yokota
Takeyasu Ito
Omori Miko