Title:
POLYPEPTIDES
Document Type and Number:
Japanese Patent JP2014138587
Kind Code:
A
Abstract:
PROBLEM TO BE SOLVED: To provide polypeptides capable of eliciting immune reaction against cancer, nucleic acids DNA encoding these polypeptides, methods for generating T lymphocytes capable of recognizing and destroying tumor cells, and pharmaceutical compositions for the treatment, prophylaxis or diagnosis of cancer.SOLUTION: Provided is a polypeptide having a specified amino acid sequence that can induce T cell response, based on the TERTγ- and σ-splicing variants. The polypeptide and the nucleic acid encoding the polypeptide are used for medicine and diagnosis.
Inventors:
GAUDERNACK GUSTAV
SAEBOE-LARSSEN STEIN
MOELLER MONA
ERIKSEN JON AMUND
SAEBOE-LARSSEN STEIN
MOELLER MONA
ERIKSEN JON AMUND
Application Number:
JP2014005980A
Publication Date:
July 31, 2014
Filing Date:
January 16, 2014
Export Citation:
Assignee:
GEMVAX AS
International Classes:
C12N15/09; A61K31/7088; A61K35/14; A61K35/76; A61K38/00; A61K38/47; A61K39/00; A61K45/00; A61K47/42; A61K48/00; A61P35/00; A61P43/00; C07K7/06; C07K14/47; C07K16/40; C12N1/15; C12N1/19; C12N1/21; C12N5/07; C12N5/0783; C12N5/09; C12N5/10; C12N9/12; C12Q1/02; C12Q1/68; G01N33/574; C12N
Foreign References:
| WO1999001560A1 | 1999-01-14 | |||
| WO2000002581A1 | 2000-01-20 |
Other References:
JPN6015011645; ＢＥＲＮＨＡＲＤＴ， Ｓ．Ｌ． ｅｔ ａｌ．: Ｂｒ． Ｊ． Ｃａｎｃｅｒ Ｖｏｌ．９５, 2006, ｐｐ．１４７４-１４８２
JPN6015011649; ＳＣＨＲＯＥＲＳ， Ｒ． ｅｔ ａｌ．: Ｃａｎｃｅｒ Ｒｅｓ． Ｖｏｌ．６２, 2002, ｐｐ．２６００-２６０５
JPN6015011652; ＭＩＮＥＶ， Ｂ． ｅｔ ａｌ．: Ｐｒｏｃ． Ｎａｔｌ． Ａｃａｄ． Ｓｃｉ． ＵＳＡ Ｖｏｌ．９７， Ｎｏ．９, 20000425, ｐｐ．４７９６-４８０１
JPN6015011655; ＣＯＬＧＩＮ， Ｌ．Ｍ． ｅｔ ａｌ．: Ｎｅｏｐｌａｓｉａ Ｖｏｌ．２， Ｎｏ．５, 200010, ｐｐ．４２６-４３２
JPN6013034323; ＷＩＣＫ， Ｍ． ｅｔ ａｌ．: Ｇｅｎｅ Ｖｏｌ．２３２, 1999, ｐｐ．９７-１０６
JPN6013034319; ＫＩＬＩＡＮ， Ａ． ｅｔ ａｌ．: Ｈｕｍａｎ Ｍｏｌｅｃｕｌａｒ Ｇｅｎｅｔ． Ｖｏｌ．６， Ｎｏ．１２, 1997, ｐｐ．２０１１-２０１９
JPN6015011639; ＳＣＨＲＯＥＲＳ， Ｒ． ｅｔ ａｌ．: Ｃｌｉｎ． Ｃａｎｃｅｒ Ｒｅｓ． Ｖｏｌ．９, 2003, ｐｐ．４７４３-４７５５
JPN6015011643; ＢＲＵＮＳＶＩＧ， Ｐ．Ｆ． ｅｔ ａｌ．: Ｃａｎｃｅｒ Ｉｍｍｕｎｏｌ． Ｉｍｍｕｎｏｔｈｅｒ． Ｖｏｌ．５５, 2006, ｐｐ．１５５３-１５６４
JPN6013034321; ＶＯＮＤＥＲＨＥＩＤＥ， Ｒ．Ｈ． ｅｔ ａｌ．: Ｉｍｍｕｎｉｔｙ Ｖｏｌ．１０, 1999, ｐｐ．６７３-６７９
JPN6015011657; 'Ｈｏｍｏ ｓａｐｉｅｎｓ ｔｅｌｏｍｅｒａｓｅ ｒｅｖｅｒｓｅ ｔｒａｎｓｃｒｉｐｔａｓｅ （ＴＥＲＴ） ｇｅｎｅ， ｅｘｏｎｓ １-６' ＧｅｎＰｅｐｔ Ａｃｃｅｓｓｉｏｎ ＡＦ１２８８９３ , 19990513
JPN6013034317; 大沢利昭ら編: 免疫学辞典（第２版） , 2001, 第９０頁
JPN6015011649; ＳＣＨＲＯＥＲＳ， Ｒ． ｅｔ ａｌ．: Ｃａｎｃｅｒ Ｒｅｓ． Ｖｏｌ．６２, 2002, ｐｐ．２６００-２６０５
JPN6015011652; ＭＩＮＥＶ， Ｂ． ｅｔ ａｌ．: Ｐｒｏｃ． Ｎａｔｌ． Ａｃａｄ． Ｓｃｉ． ＵＳＡ Ｖｏｌ．９７， Ｎｏ．９, 20000425, ｐｐ．４７９６-４８０１
JPN6015011655; ＣＯＬＧＩＮ， Ｌ．Ｍ． ｅｔ ａｌ．: Ｎｅｏｐｌａｓｉａ Ｖｏｌ．２， Ｎｏ．５, 200010, ｐｐ．４２６-４３２
JPN6013034323; ＷＩＣＫ， Ｍ． ｅｔ ａｌ．: Ｇｅｎｅ Ｖｏｌ．２３２, 1999, ｐｐ．９７-１０６
JPN6013034319; ＫＩＬＩＡＮ， Ａ． ｅｔ ａｌ．: Ｈｕｍａｎ Ｍｏｌｅｃｕｌａｒ Ｇｅｎｅｔ． Ｖｏｌ．６， Ｎｏ．１２, 1997, ｐｐ．２０１１-２０１９
JPN6015011639; ＳＣＨＲＯＥＲＳ， Ｒ． ｅｔ ａｌ．: Ｃｌｉｎ． Ｃａｎｃｅｒ Ｒｅｓ． Ｖｏｌ．９, 2003, ｐｐ．４７４３-４７５５
JPN6015011643; ＢＲＵＮＳＶＩＧ， Ｐ．Ｆ． ｅｔ ａｌ．: Ｃａｎｃｅｒ Ｉｍｍｕｎｏｌ． Ｉｍｍｕｎｏｔｈｅｒ． Ｖｏｌ．５５, 2006, ｐｐ．１５５３-１５６４
JPN6013034321; ＶＯＮＤＥＲＨＥＩＤＥ， Ｒ．Ｈ． ｅｔ ａｌ．: Ｉｍｍｕｎｉｔｙ Ｖｏｌ．１０, 1999, ｐｐ．６７３-６７９
JPN6015011657; 'Ｈｏｍｏ ｓａｐｉｅｎｓ ｔｅｌｏｍｅｒａｓｅ ｒｅｖｅｒｓｅ ｔｒａｎｓｃｒｉｐｔａｓｅ （ＴＥＲＴ） ｇｅｎｅ， ｅｘｏｎｓ １-６' ＧｅｎＰｅｐｔ Ａｃｃｅｓｓｉｏｎ ＡＦ１２８８９３ , 19990513
JPN6013034317; 大沢利昭ら編: 免疫学辞典（第２版） , 2001, 第９０頁
Attorney, Agent or Firm:
Michiharu Soga
Kajinami order
Kazuhiro Oyaku
Satoshi Iino
Kajinami order
Kazuhiro Oyaku
Satoshi Iino
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