Title:
POLYPRENYLPHENYLSULFURIC ACID DERIVATIVE
Document Type and Number:
Japanese Patent JPH01294660
Kind Code:
A
Abstract:
NEW MATERIAL:A compound expressed by formula I (R is H, lower alkyl, lower alkanoyl, tri-lower alkylsilyl or sulfo; n is 3-5 or 7-10; m is 0 or 1) or salt thereof.
EXAMPLE: Sodium salt of 3-geranyl geranyl-4-hydroxyphenyl sulfate.
USE: An anti-inflammatory agent, antiallergic agent, remedy for acute pancreatitis, gastropathy, acquired immune deficiency syndrome(AIDS), etc.
PREPARATION: A phenolic compound expressed by formula II or salt thereof is reacted with H2SO4, chlorosulfonic acid, a pyrosulfate, etc., in an inert solvent, such as carbon disulfide, pyridine or aniline, to afford the aimed compound expressed by formula I. The reaction temperature is normally while cooling heating.
More Like This:
Inventors:
YAMAMOTO HIROICHI
SHIRAKI KENJI
SHIRAKI KENJI
Application Number:
JP12479188A
Publication Date:
November 28, 1989
Filing Date:
May 21, 1988
Export Citation:
Assignee:
YAMANOUCHI PHARMA CO LTD
International Classes:
C07C305/24; A61K31/185; A61P1/00; A61P37/04; A61P43/00; C07C67/00; C07C301/00; C12N9/99; (IPC1-7): A61K31/185; C07C141/16; C12N9/99
Attorney, Agent or Firm:
Shozo Nagai (1 person outside)
Previous Patent: METHOD FOR SUPPRESSING ELIMINATING REACTION OF BLOCKED ISOCYANATE
Next Patent: PRODUCTION OF 4-ACETOXYAZETIDINONE DERIVATIVE
Next Patent: PRODUCTION OF 4-ACETOXYAZETIDINONE DERIVATIVE