Title:
ポモリン酸、その異性体、誘導体及びその使用、医薬組成物、医薬組成物の調製方法及び多剤耐性腫瘍の治療方法
Document Type and Number:
Japanese Patent JP2006504706
Kind Code:
A
Abstract:
The present invention describes the use of pomolic acid, its derivatives and pharmaceutical preparations derived from them as anti-neoplasic agents in the treatment of multidrug resistant tumors. In relation to other drugs that present anti-MDR activity, these substances do not require the concomitant use of reversers to exert their anti-MDR activities.
Inventors:
Gattas, celery, rocha
Ryum Hanek, Vivian, Marie, Dodd
Fernandez, Janina
Castillo, Rachel, Oliveira
Kaplan, Maria, Ausilia Dora, Coelo
Ryum Hanek, Vivian, Marie, Dodd
Fernandez, Janina
Castillo, Rachel, Oliveira
Kaplan, Maria, Ausilia Dora, Coelo
Application Number:
JP2004540392A
Publication Date:
February 09, 2006
Filing Date:
October 02, 2003
Export Citation:
Assignee:
Universidad Federal do Rio de Janeiro
International Classes:
A61K31/56; A61K31/192; A61P35/00; C07J63/00
Other References:
JPN6010022472, ＮＥＴＯ，Ｃ．Ｃ． ｅｔ ａｌ, "Ｃｙｔｏｔｏｘｉｃ ｔｒｉｔｅｒｐｅｎｅ ａｃｉｄｓ ｆｒｏｍ ｔｈｅ ｐｅｒｕｖｉａｎ ｍｅｄｉｃｉｎａｌ ｐｌａｎｔ Ｐｏｌｙｌｅｐｉｓ ｒａｃｅｍｏｓａ", Ｐｌａｎｔａ Ｍｅｄｉｃａ, 2000, Ｖｏｌ．６６, ｐ．４８３−４８４
Attorney, Agent or Firm:
Hideto Asamura
Hajime Asamura
Naganuma Akio
Yukihiro Ikeda
Hajime Asamura
Naganuma Akio
Yukihiro Ikeda