Title:
腫瘍の造影及び光線力学療法のためのポルフィリン化合物
Document Type and Number:
Japanese Patent JP4688709
Kind Code:
B2
Abstract:
This invention describes a first report on the synthesis of certain 124 I-labelled photosensitizers related to chlorines and bacteriochlorins with long wavelength absorption in the range of 660-800 nm. In preliminary studies, these compounds show a great potential for tumor detection by positrom emission tomography (PET) and treatment by photodynamic therapy (PDT). The development of tumor imaging or improved photodynamic therapy agent(s) itself represent an important step, but a dual function agent (PET imaging and PDT) provides the potential for diagnostic body scan followed by targeted therapy.
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Inventors:
Ravindra Kay Pandy
Munawar Sajad
Thresh pandy
Amy Grishuk
Alan Oselov
Honey Anaby
Munawar Sajad
Thresh pandy
Amy Grishuk
Alan Oselov
Honey Anaby
Application Number:
JP2006086501A
Publication Date:
May 25, 2011
Filing Date:
February 27, 2006
Export Citation:
Assignee:
Health Research,Inc.
International Classes:
C07D471/22; C07D487/22; A61K51/00; A61P35/00; A61P43/00
Domestic Patent References:
| JP2001335578A |
Other References:
Appl. Radiat. Isot.,1998年,49,955-959
Photochem. Photobiol.,1996年,64,194-204
Photochem. Photobiol.,1996年,64,194-204
Attorney, Agent or Firm:
Sadao Kumakura
Nobuo Ogawa
Atsushi Hakoda
Kenji Asai
Koji Hirayama
Nobuo Ogawa
Atsushi Hakoda
Kenji Asai
Koji Hirayama