Title:
カリウムチャネル阻害剤
Document Type and Number:
Japanese Patent JP5140597
Kind Code:
B2
Abstract:
The present invention relates to compounds having the structure useful as potassium channel inhibitors to treat cardiac arrhythmias, and the like.
Inventors:
Trotter, Wesley Bee
Nanda, Kaushik Kay
Wolkenberg, Scott
Norte, Brad M
Manley, peter
Kett, Nathan Earl
Bilodo, Mark Tay
Nanda, Kaushik Kay
Wolkenberg, Scott
Norte, Brad M
Manley, peter
Kett, Nathan Earl
Bilodo, Mark Tay
Application Number:
JP2008536718A
Publication Date:
February 06, 2013
Filing Date:
October 17, 2006
Export Citation:
Assignee:
Merck Sharp End Dome Corporation
International Classes:
C07D213/36; A61K31/437; A61K31/4375; A61K31/4439; A61K31/445; A61K31/4462; A61K31/4709; A61K31/502; A61K31/5025; A61K31/506; A61K31/5377; A61K31/538; A61P7/02; A61P9/06; A61P43/00; C07D213/54; C07D213/64; C07D213/72; C07D213/74; C07D213/75; C07D401/14; C07D405/14; C07D409/14; C07D413/14; C07D417/14; C07D471/04; C07D487/04
Domestic Patent References:
| JP4217666A | ||||
| JP2002544193A |
Foreign References:
| WO2000027824A1 | ||||
| WO2004002480A1 | ||||
| WO2003059873A1 | ||||
| WO2006060109A1 | ||||
| US6870055 |
Other References:
J. Med. Chem.,2003年,46,2413-2426
J. Med. Chem.,1970年,13,359-366
Bioorg. Med. Chem. Lett.,2002年,12,1451-1456
Phosphorus Sulfur and Silicon,1991年,55,9-17
J. Med. Chem.,1970年,13,359-366
Bioorg. Med. Chem. Lett.,2002年,12,1451-1456
Phosphorus Sulfur and Silicon,1991年,55,9-17
Attorney, Agent or Firm:
Yoshikazu Iwase
Makoto Ono
Kenkyo Kanayama
Mitsuaki Tsubokura
Kazuki Shigemori
Kenji Ando
Yasufumi Shiroyama
Makoto Ono
Kenkyo Kanayama
Mitsuaki Tsubokura
Kazuki Shigemori
Kenji Ando
Yasufumi Shiroyama