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Title:
PRAVASTATIN SODIUM
Document Type and Number:
Japanese Patent JP2005047924
Kind Code:
A
Abstract:

To provide a crystal of pravastatin sodium and a method for preparation of the crystal of pravastatin sodium.

The invention relates to the method for preparing the pravastatin sodium in a crystal state, comprises following steps, (a) preparing a solution containing pravastatin and sodium cation in a lower aliphatic alcohol (for example ethanol), (b) adding ethyl acetate to the solution, and (c) crystallizing the pravastatin sodium salt from the solution.


Inventors:
JEKKEL ANTONIA
KONYA ATTILA
BARTA ISTVAN
ILKOY EVA
SOMOGYI GYORGY
AMBRUS GABOR
HORVATH GYULA
ALBRECHT KAROLY
SZABO ISTVAN M
MOZES NEE SUTO JULIANNA
SALAT JANOS
ANDOR ATTILA
BIRINCSIK LASZLO
BOROS SANDOR
LANG ILDIKO
BIDLO NEE IGLOY MARGIT
Application Number:
JP2004254575A
Publication Date:
February 24, 2005
Filing Date:
September 01, 2004
Export Citation:
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Assignee:
INST DRUG RES LTD
International Classes:
C07B53/00; C07C61/16; C07C67/02; C07C67/28; C07C67/52; C07C69/02; C07C69/30; C07C69/33; C12N1/14; C12P7/62; C12R1/645; C07C; C12P; (IPC1-7): C07C69/30; C07C67/28; C07C67/52; C12P7/62
Attorney, Agent or Firm:
Takashi Ishida
Jun Tsuruta
Kazuhiro Nakamura
Masaya Nishiyama
Higuchi Souji