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Patent Searching and Data


Title:
PREPARATION OF ACID CHLORIDE AND ACID AMIDE
Document Type and Number:
Japanese Patent JPH07258147
Kind Code:
A
Abstract:

PURPOSE: To effectively obtain the subject compound by a novel process wherein a specific raw compound is reacted with water in the presence of a Lewis acid and a chlorocarbon solvent.

CONSTITUTION: A compound of formula I (wherein L1 and L2 are each a leaving group; and Ar is an aromatic or heteroaromatic group), [preferably a compound having Cl as L1 and L2 such as 2-chloro-6-(trichloromethyl)pyridine or the like] is reacted with water in the presence of a Lewis acid (preferably anhydrous ferric chloride) and a chlorocarbon solvent including at least two chlorine atoms (preferably 1,2-dichloroethane) to obtain the objective compound of formula II. The Lewis acid is preferably employed in a molar ratio thereof to the compound of formula I of 0.1 or less, and the compound of formula I is preferably employed in an equimolar amount to water. This reaction is preferably carried out by mixing the compound of formula I with the Lewis acid in the chlorocarbon solvent under reflux and subsequently adding water for hours to the reaction mixture under reflux.


Inventors:
MAIKERU JIYOON BURU
JIYOON WAAKATSUPU KOONFUOOSU
Application Number:
JP26624194A
Publication Date:
October 09, 1995
Filing Date:
October 05, 1994
Export Citation:
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Assignee:
SHELL INT RESEARCH
International Classes:
C07B61/00; C07C51/093; C07C51/58; C07C63/10; C07C68/00; C07C231/02; C07C233/65; C07D213/78; C07C233/66; C07C253/30; C07C255/60; C07D213/18; C07D213/54; C07D213/61; C07D213/643; C07D213/79; C07D213/803; C07D213/81; C07C; C07D; (IPC1-7): C07C51/58; C07C63/10; C07C231/02; C07C233/65; C07D213/78; C07D213/81
Attorney, Agent or Firm:
Toshiaki Ikeura (1 outside)