Title:
アントラキノン誘導体の調製
Document Type and Number:
Japanese Patent JP2006501140
Kind Code:
A
Abstract:
A compound of formula (I): in which A is a C alkylene group with a chain length between NH and N(O)R'R'' of at least 2 carbon atoms and R' and R'' are each separately selected from C1-4 alkyl groups and C2-4 hydroxyalkyl and C2-4 dihydroxyalkyl groups, or R' and R'' together are a C2-6 alkylene group, is formulated so that upon dissolution in aqueous solution the pH of the solution is in the range of 5 to 9. The compound may be in the form of salt with a physiologically acceptable acid having a pKa in the range of -3.0 (minus 3.0) to 9.0.
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Inventors:
Denny, William Alexander
Lawrence Hilton, Patterson
Halbert, Gavin William
Ford, Stephen John
Lawrence Hilton, Patterson
Halbert, Gavin William
Ford, Stephen John
Application Number:
JP2003576395A
Publication Date:
January 12, 2006
Filing Date:
March 17, 2003
Export Citation:
Assignee:
BTG International Limited
International Classes:
C07C291/04; A61K9/00; A61K31/136; A61K31/205; A61K31/21; A61K47/02; A61K47/12; A61P35/00; A61P35/02; C07C225/34; C07C225/36
Attorney, Agent or Firm:
Kazuo Shamoto
Tadashi Masui
Yasushi Kobayashi
Akio Chiba
Hiroyuki Tomita
Hiroaki Noya
Tadashi Masui
Yasushi Kobayashi
Akio Chiba
Hiroyuki Tomita
Hiroaki Noya