Title:
PREPARATION OF COENZYME Q
Document Type and Number:
Japanese Patent JPS5770834
Kind Code:
A
Abstract:
PURPOSE: To prepare coenzyme Q useful as a remedy for cardiac insufficiency, rapidly, without side reactions, with simple operation, by the catalytic oxidation of reduced coenzyme Q in a hydrophobic solvent using manganese dioxide.
CONSTITUTION: Coenzyme Q is pepared by the catalytic oxidation of reduced coenzyme Q of formula (n is integer 1W12) (2,3-dimethyoxy-5-methyl-6-prenyl hydroquinone) in a hydrophobic solvent (e.g. nexane, petroleum ether, etc.) with manganese dioxide. The concentration of the reduced coenzyme Q is usually 1W20w/v%, pref. 10w/v%, and the reaction temperature is pref. 10W40°C.
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Inventors:
KIMIZUKA FUSAO
MATSUNAGA HISAO
OOHAYASHI AKIRA
TANABE OSAMU
MATSUNAGA HISAO
OOHAYASHI AKIRA
TANABE OSAMU
Application Number:
JP14611480A
Publication Date:
May 01, 1982
Filing Date:
October 17, 1980
Export Citation:
Assignee:
TAKARA SHUZO CO
TAIHO PHARMACEUTICAL CO LTD
TAIHO PHARMACEUTICAL CO LTD
International Classes:
C07C50/28; C07C45/00; C07C46/06; C07C67/00; (IPC1-7): C07C46/06; C07C50/28
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