Title:
PREPARATION OF DIACETONE KETOGULONIC ACID ESTER
Document Type and Number:
Japanese Patent JPS5594395
Kind Code:
A
Abstract:
PURPOSE: To prepare the title compound useful as an intermediate of L-ascorbic acid for medical use, economically, in an industrial scale, by oxidizing diacetonesorbose with oxygen(-containing) gas, in an alcohol, in the presence of a Pd-containing catalyst.
CONSTITUTION: The objective diacetone ketogulonic acid ester of formula II (R1,2 are H, lower alkyl, aryl, etc.; R3 is lower alkyl) is prepared by oxidizing diacetonesorbose of formula I in an alcohol solvent with an oxygen(-containing) gas, in the presence of a Pd-containing catalyst. The catalyst pref. contains Pd and at least one metal (compound) selected from Pb, Hg, and Tl.
EFFECT: The reaction can be carried out in one step.
Inventors:
NISHIKIDO JIYOUJI
FUKUOKA YOUHEI
TAMURA WATAHIKO
FUKUOKA YOUHEI
TAMURA WATAHIKO
Application Number:
JP97879A
Publication Date:
July 17, 1980
Filing Date:
January 11, 1979
Export Citation:
Assignee:
ASAHI CHEMICAL IND
International Classes:
C07H9/04; B01J23/00; B01J23/44; B01J23/60; B01J23/62; B01J27/00; B01J27/13; B01J27/25; C07B61/00; (IPC1-7): B01J23/60; B01J23/62; C07H9/04