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Title:
PREPARATION FOR EXTERNAL USE AND INCREASE OF PERCUTANEOUS OR TRANSMUCOSAL ABSORPTION
Document Type and Number:
Japanese Patent JPH1180031
Kind Code:
A
Abstract:
PROBLEM TO BE SOLVED: To obtain a preparation for external use which increases the percutaneous or transmucosal absorption of medicines and is high in the safety and to provide a method for increasing the percutaneous or transmucosal absorption of medicines. SOLUTION: This preparation for external use is obtained by blending a medicine (e.g. salicylic acid) with a scrub (e.g. crushed pieces of apricot endocarp). The medicine is an antifungal (e.g. miconazole nitrate), a local anesthetic (e.g. ethyl 4-aminobenzoate), an anti-inflammatory analgesic (e.g. indomethacin) or urea. As the dosage form, ointment, cream, gel agent, liniment, emulsion, powder and foam agent are preferable The percutaneous or transmucosal absorption of the medicine is increased by adding the scrub to the base including the medicine.

Inventors:
WATABE MITSUAKI
SHIMIZU TATSUTAKE
MATSUDA MASANORI
ABE YOSHIKO
Application Number:
JP748798A
Publication Date:
March 23, 1999
Filing Date:
January 19, 1998
Export Citation:
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Assignee:
SEKISUI CHEMICAL CO LTD
International Classes:
A61K9/06; A61K31/135; A61K31/17; A61K31/405; A61K31/415; A61K31/60; A61K45/00; A61K47/46; A61P25/02; A61P25/04; A61P29/00; A61P31/04; A61P31/10; (IPC1-7): A61K47/46; A61K9/06; A61K31/17; A61K31/405; A61K31/415; A61K31/60; A61K45/00