Login| Sign Up| Help| Contact|

Patent Searching and Data


Title:
PREPARATION IN WHICH SACCHARIDES DIFFERENT IN PARTICLE DIAMETER IS FORMULATED
Document Type and Number:
Japanese Patent JP2004175690
Kind Code:
A
Abstract:

To produce a granulated substance in which a ratio of crude particles is reduced by a fluidized bed granulating machine and the content segregation of a medicine is small.

Powder for fluidized bed granulation comprises at least two kinds of saccharides different by ≥5 times in particle diameter and a medicine. The granulated substance having small content segregation of the medicine can be produced by granulating the powder for fluidized bed granulation by using the fluidized bed granulating machine. In the granulated substance, the ratio of crude particles remaining on a sieve having ≥500 μm sieve opening is slight and the ratio is ≤15% and a medicine content in every particle size which becomes an index of the content segregation of the medicine is 80-130% and the difference between the maximum value and the minimum value of the content is within 45%.


Inventors:
YOSHIDA TATSUMORI
FUNAKI KENJI
Application Number:
JP2002341230A
Publication Date:
June 24, 2004
Filing Date:
November 25, 2002
Export Citation:
Click for automatic bibliography generation   Help
Assignee:
SHIONOGI & CO
International Classes:
A61K47/26; A61K9/08; A61K9/10; A61K9/14; A61K9/20; A61K9/48; (IPC1-7): A61K47/26; A61K9/08; A61K9/10; A61K9/14; A61K9/20; A61K9/48
Attorney, Agent or Firm:
Hideaki Yamauchi
Kenichi Sugita