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Title:
PREPARATION OF MICROCAPSULE CONTAINING LIQUID ACTIVE SUBSTANCE
Document Type and Number:
Japanese Patent JPS60125245
Kind Code:
A
Abstract:

PURPOSE: To prepare a microcapsule having an oxidation inhibitor sealed therein, by dissolving a polymer, the liquid active substance and the oxidation inhibitor in an org. solvent having volatility easier than that of the liquid active substance while spraying the obtained solution in a liquid droplet form.

CONSTITUTION: A polymer such as polysulfone, an active substance (e.g., Z-11- hexadecenal) having a limited solubility to the polymer at an ambient temp. and liquid at an ambient temp. and an oxidation inhibitor (e.g., 2,6-di-t-butyl-4-phenol) are dissolved in an org. solvent (e.g., methylene chloride) capable of dissolving all of the active substance, the oxidation inhibitor and polymer and having volatility easier than that of the active substance. This solution is sprayed as fine liquid droplets from a nozzle and the solvent is evaporated from the liquid droplets to dry said liquid droplets and a microcapsule, wherein the liquid active substance and the oxidation inhibitor are sealed in the polymer skin film, is obtained. As a result, the chemically unstable liquid active substance can be kept stably over a long period of time.


Inventors:
NINOMIYA YASUO
KOMAMURA CHIAKI
MUSA GIICHI
Application Number:
JP23468883A
Publication Date:
July 04, 1985
Filing Date:
December 12, 1983
Export Citation:
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Assignee:
NITTO ELECTRIC IND CO
International Classes:
A01N25/28; A61K9/58; B01J13/04; B01J13/12; (IPC1-7): A01N25/28; B01J13/02
Domestic Patent References:
JPS5834034A1983-02-28
JPS4890977A1973-11-27
JP35009197A
JPS5695101A1981-08-01
JPS56104802A1981-08-20
Attorney, Agent or Firm:
Ichiro Makino