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Title:
生存菌類寄生微生物ピシウム・オリガンドラムを含む、皮膚および粘膜の皮膚糸状菌症および酵母感染症の処置用製剤、微生物ピシウム・オリガンドラムの細胞生存率を決定する方法ならびに該製剤の適用方法
Document Type and Number:
Japanese Patent JP6667501
Kind Code:
B2
Abstract:
A preparation containing the mycoparasitic microorganism Pythium oligandrum for the treatment of dermatophytoses and yeast infections on the skin and mucous membranes obtained from a dry mixture containing 0.1 to 99.9% weight mycoparasitic microorganism Pythium oligandrum and 0.1 to 99.9% auxiliary substances, containing at least one component from a group comprising adsorbent, buffer, moisturizer, deodorant and aroma. This preparation contains 1 to 10×106, with preference of 10 to 50, viable cells of the Pythium oligandrum microorganism per 1 ml of aqueous suspension at the site of applying the preparation, whereby the viable cells of the Pythium oligandrum microorganism comprise dormant oospores, encysted zoospores and viable coenocytic mycelium. Different application methods of using the preparation are claimed. Exemplary embodiments show the viability of cells using genetic tests and practical tests conducted under the supervision of dermatologists, stomatologists and veterinarians.

Inventors:
Schanek, Martin
Klimes, Laden
Application Number:
JP2017504824A
Publication Date:
March 18, 2020
Filing Date:
August 22, 2016
Export Citation:
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Assignee:
Bio-Agens Research and Development-Bird, S.R.O.
International Classes:
A61K36/06; A61K9/08; A61K9/10; A61K47/04; A61K47/06; A61K47/10; A61K47/12; A61K47/26; A61P1/02; A61P17/00; A61P31/10
Domestic Patent References:
JP2013510100A
JP55022668A
Foreign References:
CZ28816B6
WO2016112881A1
WO1998016110A1
Other References:
Mycologia, 2006, Vol.98 No.3, p.410-422
Ann appl Biol., 1990, Vol.116, p.205-212
FEMS Microbiol Ecol., 2000, Vol.33, p.139-146
Attorney, Agent or Firm:
Atsushi Nakajima
Kato Kazunori