To provide a pressure regulator capable of setting arbitrary pressure in all pressure regions from a high pressure region to a normal pressure region and sufficiently increasing compressed air flow rate in the normal pressure region, and a compressed air take-out device.

This pressure regulator is constituted of an opening/closing valve 34 for opening/closing between a primary side port 32 connected to a compressed air source of high pressure and a secondary side port 33 connected to a tool side, a piston 39 arranged on a downstream side of the opening/closing valve 34 and formed with a pressure receiving surface 37 for receiving secondary side air pressure, a pressure adjusting spring 40 for pressing the piston 39 to face the piston 39 to the pressure receiving surface 37 and an adjusting means 46 for varying and setting spring force of the pressure adjusting spring 40. The pressure adjusting spring 40 is constituted by mounting two adjusting springs 41 and 42 having different spring constants in series.