PURPOSE: To provide the subject adhesive composed of a specific pressure- sensitive adhesive structure coordinated with sugar, applicable to the skin without causing the rash and itchiness and having excellent safety, adhesiveness, feeling to the skin, water-absorption and compatibility to the skin.
CONSTITUTION: The objective adhesive contains preferably ≥5wt.%, especially 10-50wt.% of a pressure-sensitive adhesive structure containing a sugar having a molecular weight of ≥150 (e.g. glucose) coordinated to ≥1wt.% of the ester part of a copolymer containing one or more kinds of acrylic acid esters. The adhesive is preferably incorporated with 1-50wt.% of an agent such as hydrocortisone and formed on a flexible substrate to obtain a pharmaceutical preparation.
OTSUKA SABURO
KINOSHITA TAKASHI
