Prevention of rheumatoid arthritis or a constituent for medical treatment which contains a monoacetyl diacyl glycerol compound as an active ingredient

Japanese Patent JP6081024

B2

The invention relates to pharmaceutical compositions, as well as health functional food compositions and quasi-drug compositions, for preventing, treating, or improving rheumatoid arthritis, comprising a monoacetyldiacylglycerol compound as an active ingredient. The monoacetyldiacylglycerol of the invention is effective in inhibiting the phosphorylation of STAT-3 known to be a therapeutic target for rheumatoid arthritis. As the monoacetyldiacylglycerol is an effective therapeutic agent without toxicity, the monoacetyldiacylglycerol can overcome the side effects of the medicines currently used in the treatment of rheumatoid arthritis. Thus, the monoacetyldiacylglycerol can be used for preventing, treating or improving rheumatoid arthritis.

JP5198063	New biocleavable linker
JPS61197522	LIPID COMPOSITION
WO/2021/020514	COLLAGEN PRODUCTION PROMOTER, WRINKLE AMELIORATING AGENT, EXTERNAL PREPARATION FOR SKIN, AND COSMETIC FOOD OR BEVERAGE

Kim jeffa
Oselyan
Ankyung Sup
Khan Hobom
Park Bombs
Itseoku
Kang Jong
Jeong Young-sik
Han Younghae
Song Kiyoung

JP2016536022A

February 15, 2017

August 18, 2014

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ENZYCHEM LIFESCIENCES CORPORATION
KOREA RESEARCH INSTITUTE OF BIOSCIENCE AND BIOTECHNOLOGY

A61K31/23; A23L33/12; A61K35/36; A61P19/02; A61P29/00; A61P43/00

JP2007534681A
JP2013544802A
JP2013530999A

Kenichi Morita
Kenjiro Yamaguchi
Hironori Nagayama
Yuzaki Ozaki

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