Title:
PREVENTION OR TREATMENT OF SLEEP DISORDERS USING DEXMEDETOMIDINE FORMULATION
Document Type and Number:
Japanese Patent JP2021080276
Kind Code:
A
Abstract:
To provide a composition suitable for oral transmucosal administration (sublingual) comprising dexmedetomidine.SOLUTION: A composition is useful for the treatment of sleep disorders such as insomnia and capable of providing sleep on demand. The composition comprises an effective amount of dexmedetomidine or pharmaceutically acceptable salts thereof, solvates thereof, or derivatives thereof, formulated for delivery of dexmedetomidine across a subject's oral mucosa.SELECTED DRAWING: Figure 1
Inventors:
HARSH NEGI
DEEPA SAINI
SAMEER SHARMA
KRISHNAN NANDABALAN
FRANK YOCCA
DEEPA SAINI
SAMEER SHARMA
KRISHNAN NANDABALAN
FRANK YOCCA
Application Number:
JP2021025810A
Publication Date:
May 27, 2021
Filing Date:
February 22, 2021
Export Citation:
Assignee:
BIOXCEL THERAPEUTICS INC
International Classes:
A61K31/4174; A61K9/12; A61K9/20; A61K9/70; A61P25/20; A61P43/00
Domestic Patent References:
| JP2011506337A | 2011-03-03 | |||
| JP2010516684A | 2010-05-20 | |||
| JP2012526854A | 2012-11-01 | |||
| JP2009526829A | 2009-07-23 |
Foreign References:
| US20100196286A1 | 2010-08-05 |
Other References:
BR.J.CLIN.PHARMACOL., vol. 56, JPN6020040401, 2003, pages 691 - 693, ISSN: 0004713018
Attorney, Agent or Firm:
Yoshiyuki Inaba
Toshifumi Onuki
Akihiko Eguchi
Kazuhiko Naito
Toshifumi Onuki
Akihiko Eguchi
Kazuhiko Naito