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Title:
炎症性気道疾患の予防・治療剤
Document Type and Number:
Japanese Patent JP3691487
Kind Code:
B2
Abstract:
A preventive and/or therapeutic agent for inflammatory respiratory tract diseases containing, as an active ingredient, a steroid derivative represented by the following formula (1): (wherein R represents a hydrogen atom, a halogen atom, a hydroxy group, or -OCOR<1> (wherein R<1> represents a linear or branched alkyl group which may be substituted by a halogen atom or a cycloalkyl group; a cycloalkyl group; or an aryl group)). These compounds can continuously suppress respiratory tract inflammation and respiratory tract hyperreaction and show a high site selectivity and little systemic effect when administered directly to the respiratory tract. By virtue of these characteristics, these compouds are remarkably useful in clinical medicine as highly safe preventive and/or therapeutic agents for inflammatory respiratory tract diseases which can be administered for a long period of time.

Inventors:
Teruo Komoto
Hiroyuki Mizuno
Takahashi Miki
Koichi Takahashi
Susumu Sato
Application Number:
JP2002552566A
Publication Date:
September 07, 2005
Filing Date:
December 21, 2001
Export Citation:
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Assignee:
Hisamitsu Medical Co., Ltd.
International Classes:
A61K31/57; A61K31/573; A61P11/06; A61P27/16; C07J5/00; C07J7/00; (IPC1-7): A61K31/573; A61P11/00; A61P11/02; A61P11/04; A61P11/06; A61P27/16; A61P29/00; A61P37/08
Domestic Patent References:
JP2279694A
JP9501700A
JP2004512359A
Foreign References:
WO2002047667A1
Attorney, Agent or Firm:
Alga Patent Office, a patent business corporation
Miyuki Ariga
Toshio Takano
Toshio Nakajima
Masaki Murata
Hiroto Yamamoto
Asano Yasutaka
Hiromi Matoba
Ohno Shiki