Title:
9α,21―ジハロ―プレグナン―11β,17α―ジオール―20―オンの17―エステルの調製のためのプロセス
Document Type and Number:
Japanese Patent JP4269110
Kind Code:
B2
Abstract:
The invention provides an improved process for the preparation of 17-esters of 9 alpha ,21-dihalo-pregnane-11 beta ,17 alpha -diol-20-ones, and in particular for the preparation of 17-esters of anti-inflammatory steroids according to the above-mentioned scheme, wherein RCO, R<1>, X, Y and the dotted line are as defined in the specification. The novel process is especially suitable for the preparation of Mometasone Furoate.
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Inventors:
Quoc, Dow-ion Albert
Rhino, David Jay S.
Tan, butterfly
Fu, Zaoyeon
Rhino, David Jay S.
Tan, butterfly
Fu, Zaoyeon
Application Number:
JP50414798A
Publication Date:
May 27, 2009
Filing Date:
June 25, 1997
Export Citation:
Assignee:
Schering Corporation
International Classes:
C07J7/00; C07J71/00; C07J75/00
Domestic Patent References:
| JP57146800A |
Foreign References:
| US2713587 | ||||
| US2793207 | ||||
| US3440252 | ||||
| US3502700 |
Attorney, Agent or Firm:
Hidesaku Yamamoto
Takaaki Yasumura
Natsuki Morishita
Takaaki Yasumura
Natsuki Morishita