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Title:
PROCESS FOR PREPARATION OF 17-ESTERS OF 9α,21-DIHALO-PREGNANE-11β,17α-DIOL-20-ONES
Document Type and Number:
Japanese Patent JP2012149076
Kind Code:
A
Abstract:

To provide a process for the preparation of 17-esters of 9 α,21-dihalo-pregnane-11β,17α-diol-20-ones.

The process for the preparation of related 17-esters, represented by the following formula, includes reacting 17α-hydroxy of 9α,21-dihalo-pregnane-11β,17α-diol-20-ones with 2-furoyl chloride. The compound is useful as an anti-inflammatory.


Inventors:
Kwok, Daw-iong Albert
Tsai, David J. S.
Tann, Chou-hong
FU, Xiaoyong
Application Number:
JP2012000062497
Publication Date:
August 09, 2012
Filing Date:
March 19, 2012
Export Citation:
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Assignee:
SCHERING CORP
International Classes:
C07J17/00; A61K31/58; A61P29/00; C07J7/00; C07J71/00
Attorney, Agent or Firm:
山本 秀策
安村 高明
森下 夏樹