Title:
PROCESS FOR PREPARING *11OXOO22PHENYL* HALOPHENYL OR THIENYLL22MEHYLL 6*77DICHLOROOINDANYLOXY*ACETATE
Document Type and Number:
Japanese Patent JPS51125057
Kind Code:
A
Abstract:
Process for preparing (1-oxo-2-phenyl, halophenyl or thienyl-2-methyl-6,7-dichloro-5-indanyloxy)acetic acid, pharmaceutically acceptable salt, ester and amide derivatives thereof and intermediate 5-ether derivatives thereof comprising reacting under Friedel-Crafts conditions a 2-phenyl, halophenyl or thienyl-2-propionyl halide or an anhydride thereof with an ether derivative of 2,3-dichlorophenyl; and reacting the resulting propiophenone with formaldehyde in the presence of acid to yield the desired indanone.
Inventors:
UOOREN KEE RASU JIYUNIA
JIYOOJI JII HEIZEN
AARU EMU CHIEIMUBAARIN
JIYOOJI JII HEIZEN
AARU EMU CHIEIMUBAARIN
Application Number:
JP11698874A
Publication Date:
November 01, 1976
Filing Date:
October 11, 1974
Export Citation:
Assignee:
MERCK & CO INC
International Classes:
A61K31/12; A61K31/19; A61K31/22; A61P7/10; A61P19/06; C07C45/46; C07C45/66; C07C45/75; C07C49/755; C07C49/84; C07C51/00; C07C51/367; C07C59/125; C07C59/90; C07C67/00; C07D211/46; C07D333/22; (IPC1-7): A61K31/19; A61K31/38; C07C65/20; C07D257/04
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