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Title:
セフポドキシムプロクセチルジアステレオ異性体の調製プロセス
Document Type and Number:
Japanese Patent JP3911124
Kind Code:
B2
Abstract:
A process for increasing the diastereoisomeric ratio (B/A+B), wherein B is the more apolar and A is the more polar of two diastereoisomers, of a mixture of diastereoisomers of a compound of formulathe diastereoisomers being with respect to the carbon atom marked with a star in formula I, comprising treating a mixture of diastereoisomers of a compound of formula I with alcohol and water and isolating the precipitated compound of formula I in an increased diastereoisomeric ratio (B/A+B) of 0.5 to 0.6.

Inventors:
Greer, Yulia
Rudetshear, Johannes
Klaus Thoth Schneich
Wolf, Siegfried
Application Number:
JP2000527547A
Publication Date:
May 09, 2007
Filing Date:
January 07, 1999
Export Citation:
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Assignee:
SANDOZ AKTIENGESELLSCHAFT
International Classes:
C07D501/12; C07D501/00; C07D501/34; C07C227/34
Domestic Patent References:
JP5178861A
JP324086A
JP1249778A
Other References:
S.T.P.Pharma Sciences,1995年,Vol.5, No.4,p.324-331
Attorney, Agent or Firm:
Yoshio Kawaguchi
Akio Ichiiri
Makoto Ono
Katsuma Osaki
Mitsuaki Tsubokura