キサンチンホスホジエステラーゼVインヒビターおよびその前駆物質を調製するプロセス

Japanese Patent JP2005529934

A

A process for preparing xanthine phosphodiesterase V inhibitors, and compounds utilized in said process. The process includes a five-step methodology for efficient synthesis of Compound 5 without intermediate purifications or separations, a dihalogenation step to synthesize Compound 7, and a coupling reaction to produce Compound 9.

JPH1072407	PRODUCTION OF CHLOROFORMIC ACID ESTER
JPS5263890	HIGHHMOLECULAR INSOLUBLE CARBODIIMIDO CATALYSTS AND MANUFACTURE
WO/1991/016283	ENVIRONMENTALLY SAFE CATALYTIC ALKYLATION USING LIQUID ONIUM POLY (HYDROGEN FLUORIDES)

Dahanukkah, Villa H.
Nguyen, Hoa N.
All, Cecilia A.
Zhang, Fucheng
Xavi Love, Iria A.

JP2004509683A

October 06, 2005

May 30, 2003

Click for automatic bibliography generation  

Schering Corporation

C07B61/00; C07C257/12; C07D233/90; C07D473/06; (IPC1-7): C07D473/06; C07D233/90

JPH1059969A	1998-03-03
JPH051065A	1993-01-08
JPH09510983A	1997-11-04
JPH04128285A	1992-04-28
JPH0372480A	1991-03-27
JPH0374369A	1991-03-28
JP2004043429A	2004-02-12

WO2002024698A1

2002-03-28

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JPN6009061614, ＢＲＩＤＳＯＮ，Ｐ．Ｋ．　ｅｔ　ａｌ, "１−Ｓｕｂｓｔｉｔｕｔｅｄ　ｘａｎｔｈｉｎｅｓ", Ｓｙｎｔｈｅｓｉｓ, 1995, Ｎｏ．７, ｐｐ．８５５−８５８

Hidesaku Yamamoto
Takaaki Yasumura
Natsuki Morishita

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