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Title:
PROCESSES AND INTERMEDIATES FOR THE PREPARATION OF 1'-SUBSTITUTED CARBA-NUCLEOSIDE ANALOGS
Document Type and Number:
Japanese Patent JP2015180682
Kind Code:
A
Abstract:
PROBLEM TO BE SOLVED: To provide processes and intermediates for preparation of compounds having antiviral activity.SOLUTION: Provided are processes and intermediates for the syntheses of nucleosides of pyrrolo[1,2-f][1,2,4]triazinyl and imidazo[1,2-f][1,2,4]triazinyl heterocycles of Formula I.

Inventors:
THOMAS BUTLER
CHO AESOP
BENJAMIN R GRAETZ
KIM CHOUNG U
SAMUEL E METOBO
OLIVER L SAUNDERS
ANDREW W WALTMAN
XU JIE
ZHANG LIJUN
Application Number:
JP2015118067A
Publication Date:
October 15, 2015
Filing Date:
June 11, 2015
Export Citation:
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Assignee:
GILEAD SCIENCES INC
International Classes:
C07H7/02; C07H7/06; C07H9/04; C07H15/18; C07H23/00
Domestic Patent References:
JP2004502780A2004-01-29
JP2008501792A2008-01-24
Foreign References:
WO2009132135A12009-10-29
WO2004111050A12004-12-23
WO2005033121A22005-04-14
Other References:
JPN6016032315; CHAMORRO, C. et al.: 'Exploring the role of the 5'-position of TSAO-T. Synthesis and anti-HIV evaluation of novel TSAO-T d' Antiviral Research 50(3), 2001, pp. 207-222
Attorney, Agent or Firm:
Shinjiro Ono
Yasushi Kobayashi
Shigeo Takeuchi
Osamu Yamamoto
Hiroko Ejiri