Title:
PROCESSES FOR PREPARATION OF S1P1 RECEPTOR MODULATORS AND CRYSTALLINE FORMS THEREOF
Document Type and Number:
Japanese Patent JP2015180706
Kind Code:
A
Abstract:
PROBLEM TO BE SOLVED: To provide processes for preparation of S1P1 receptor modulators and crystalline forms thereof.SOLUTION: The present invention relates to salts, processes, and process intermediates useful in the preparation of (R)-2-(9-chloro -7-(4-isopropoxy-3-(trifluoromethyl)benzyloxy)-2,3-dihydro-1H-pyrrolo[1,2-a]indole-1-yl)acetic acid of formula (Ia), and salts and crystalline forms thereof.
Inventors:
JONES ROBERT M
DANIEL J BUZARD
TAWFIK GHARBAOUI
BENJAMIN R JOHNSON
MICHELLE KASEM
THOMAS O SCHRADER
SCOTT STIRN
DANIEL J BUZARD
TAWFIK GHARBAOUI
BENJAMIN R JOHNSON
MICHELLE KASEM
THOMAS O SCHRADER
SCOTT STIRN
Application Number:
JP2015142650A
Publication Date:
October 15, 2015
Filing Date:
July 17, 2015
Export Citation:
Assignee:
ARENA PHARM INC
International Classes:
C07D487/04; A61K31/407; A61P1/04; A61P1/16; A61P3/10; A61P5/00; A61P9/10; A61P13/12; A61P17/06; A61P17/10; A61P21/00; A61P25/00; A61P29/00; A61P37/06; A61P43/00
Attorney, Agent or Firm:
Hidesaku Yamamoto
Natsuki Morishita
Natsuki Morishita
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