To provide a fluid control processing system capable of adapting the measurement and distribution of fluid in a device to various protocols.

A fluid control processing system for controlling the flow of the fluid among a plurality of chambers includes a main body including a fluid processing region 30 continuously fluidly coupled to a fluid displacement region 50. The fluid displacement region can be depressurized to draw the fluid into the fluid displacement region and pressurized to expel the fluid from the fluid displacement region. The main body includes at least one external port 42. The fluid processing region is fluidly coupled to at least one external port of the main body. The main body is adjustable with respect to the plurality of chambers to place at least one external port selectively in fluidic communication with the plurality of chambers. One or more of the chambers may be a processing chamber including two ports configured to be selectively engaged with at least one external port of the main body, and a fluid processing material such as an enrichment material or a depletion material.