Title:
PRODRUG OF 9-AMINOMETHYL TETRACYCLINE COMPOUND
Document Type and Number:
Japanese Patent JP2011042666
Kind Code:
A
Abstract:
To provide a prodrug of a 9-aminomethyl-substituted tetracycline compound, to provide a method for using the compound, and to provide a pharmaceutical composition containing the same.
The prodrug of the 9-aminomethyl-substituted tetracycline compound is represented by, e.g. formula (I) (wherein, E is oxygen, nitrogen, or a covalent bond; and G is alkyl; heterocyclic alkyl; aryl; alkylcarbonyloxyalkyl; arylcarbonyloxyalkyl; alkyloxycarbonyloxyalkyl; arylalkylcarbonyloxyalkyl; alkyloxyalkylcarbonyloxyalkyl; or alkoxyalkoxycarbonyloxyalkyl).
Inventors:
KWASI OHEMENG
AMOO VICTOR
KIM OAK
BOWSER TODD
ASSEFA HAREGEWEIN
BHATIA BEENA
BERNIAC JOEL
CHEN JACKSON
GRIER MARK
HONEYMAN LAURA
PAN JINGWEN
MECHICHE RACHID
AMOO VICTOR
KIM OAK
BOWSER TODD
ASSEFA HAREGEWEIN
BHATIA BEENA
BERNIAC JOEL
CHEN JACKSON
GRIER MARK
HONEYMAN LAURA
PAN JINGWEN
MECHICHE RACHID
Application Number:
JP2010229213A
Publication Date:
March 03, 2011
Filing Date:
October 12, 2010
Export Citation:
Assignee:
PARATEK PHARM INNC
International Classes:
C07C237/26; A61K31/65; A61P3/10; A61P9/10; A61P11/00; A61P13/00; A61P13/02; A61P17/02; A61P19/02; A61P19/10; A61P25/14; A61P25/28; A61P27/02; A61P29/00; A61P31/04; A61P31/10; A61P31/12; A61P33/06; A61P35/00; A61P35/04; A61P43/00; C07C271/22; C07C271/54; C07C275/28; C07C275/30; C07D211/18; C07D317/40
Domestic Patent References:
| JPH11209337A | 1999-08-03 | |||
| JP2002105038A | 2002-04-10 | |||
| JP2004537544A | 2004-12-16 | |||
| JP2004502752A | 2004-01-29 | |||
| JP2005504722A | 2005-02-17 | |||
| JP2005526754A | 2005-09-08 | |||
| JP2006503898A | 2006-02-02 | |||
| JP2006503897A | 2006-02-02 | |||
| JP2007521290A | 2007-08-02 | |||
| JP2000504313A | 2000-04-11 |
Foreign References:
| WO2003005971A2 | 2003-01-23 | |||
| WO2002004406A2 | 2002-01-17 | |||
| WO2002072031A2 | 2002-09-19 |
Attorney, Agent or Firm:
Hatsushi Shimizu
Koichi Niimi
Koichi Niimi