To obtain the subject compound useful as an intermediate for synthesizing medicines, agrochemicals, etc., by reacting 2-chloro-4-tri, di or monochloromethylpyridine with an amine and hydrogen in the presence of a catalyst for hydrogenation.

This 2-chloro-4-aminomethylpyridine, expressed by formula II, useful as an intermediate for synthesizing medicines and agrochemicals, e.g. as an intermediate for synthesizing histamine-H2 receptor antagonists, is obtained in high yield and purity in an industrially advantageous way by reacting 2-chloro-4-trichloromethylpyridine, 2-chloro-4-dichloromethylpyridine or 2-chloro-4-chloromethylpyridine or a mixture of these pyridine derivatives with an amine (e.g. piperidine) expressed by formula I [R1 and R2 are each H, a (substituted) alkyl, an aryl, an aralkyl, or form a (substituted) 4-8 membered ring together with a nitrogen atom bound to either of these groups.] and hydrogen in the presence of a catalyst for hydrogenation (e.g. Raney nickel).