Title:
4-ハロアルキルニコチン酸エステルの製造
Document Type and Number:
Japanese Patent JP2005504791
Kind Code:
A
Abstract:
A process for preparing 4-haloalkylnicotinic esters of the formula (I), where RF is (C1-C4)-haloalkyl and R is (C1-C6)-alkyl; which comprises a) reacting an aminoketone of the formula (II), RF-C(O)-CH-CH-NH2 (II) in a condensation reaction under reduced pressure with a compound of the formulae (III) to (V), (R1Z)CH-CH-COOR (III), (R1Z)2CH-CH2-COOR (IV), HC≡C-COOR (V), where R1 is (C1-C6)-alkyl and Z is O, S, NR1 or C(O)O, to give a compound of the formulae (VI) and/or (VII), RF-C(O)-CH-CH-NH-CH-CH-COOR (VI) RF-C(O)-CH-CH-NH-CH(ZR1)-CH2-COOR (VII) b) and subjecting the reaction product to a ring closure reaction.
Inventors:
Sergey Paseknock
Application Number:
JP2003526894A
Publication Date:
February 17, 2005
Filing Date:
July 25, 2002
Export Citation:
Assignee:
Bayer Crop Science Game Behr
International Classes:
A01N43/40; C07B61/00; C07C69/54; C07C225/14; C07D213/803; C07C227/06; C07C227/08; C07C229/30; C07D211/76; C07D211/86; C07D213/80; C07D213/82; (IPC1-7): C07D213/803; C07D213/82
Attorney, Agent or Firm:
Chika Takagi
Junji Yuda
Shoji Miwa
Junji Yuda
Shoji Miwa