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Patent Searching and Data


Title:
PRODUCTION OF 4-HYDROXYPHENYLGLYOXYLIC ACIDS
Document Type and Number:
Japanese Patent JPH05194309
Kind Code:
A
Abstract:

PURPOSE: To produce 4-hydroxyphenylglyoxylic acids useful as intermediates for various organic fine chemicals such as pharmaceuticals and agricultural chemicals from an inexpensive raw material in high yield and selectivity.

CONSTITUTION: The objective compound of formula II can be produced on an industrial scale at a low cost by oxidizing 1-(4-hydroxyphenyl)-2-hydroxy-1- ethanone of formula I (R1 to R4 are substituent inert to reaction site, e.g. H, OH, 1-4C alkyl or alkoxy) with molecular oxygen in an aqueous solvent under basic condition (e.g. in an aqueous solution of a basic substance such as NaOH, KOH and Na2CO3) in the presence of a catalyst containing platinum-group element (preferably Pt or Pd, especially Pt) preferably at 0-100°C (especially 20-70°C). The compound of formula I used as a raw material is easily synthesizable by condensing inexpensive phenols with glyoxal in the presence of a basic substance or an acidic substance.


Inventors:
Moriyasu, Masataka
Maki, Takao
Araki, Yoshitake
Application Number:
JP1992000009485
Publication Date:
August 03, 1993
Filing Date:
January 22, 1992
Export Citation:
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Assignee:
MITSUBISHI KASEI CORP
International Classes:
B01J23/44; C07B61/00; C07C51/23; C07C59/84; (IPC1-7): B01J23/44; C07B61/00; C07C51/23; C07C59/84
Attorney, Agent or Firm:
長谷川 一 (外1名)