Title:
PRODUCTION OF 5-AMINO-2-CHLORO-4-FLUOROTHIOPHENOL AND INTERMEDIATE THEREFOR
Document Type and Number:
Japanese Patent JPH04108770
Kind Code:
A
Abstract:
PURPOSE: To obtain a compound useful as a synthetic intermediate for thidiazacyclononane-based herbicides in good yield by reducing S-(2-chloro-4- fluoro-5-nitrobenzene)thioacetate and then hydrolyzing the reduced compound.
CONSTITUTION: 2-Chloro-4-fluoro-5-nitrobenzenesulfonyl chloride used as a raw material is reacted in the presence of red phosphorus and iodine in acetic acid to afford S-(2-chloro-4-fluoro-5-nitrobenzene)thioacetate, which is then reduced by iron powder and mineral acid to give S-(5-amino-2-chloro-4-fluorobenzene)- thioacetate. Then the compound is hydrolyzed with an inorganic base (e.g. NaOH) to provide the objective 5-amino-2-chloro-4-fluorothiophenol.
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Inventors:
NAGATA TOSHIHIRO
KIMOTO TAKAHIRO
KIMOTO TAKAHIRO
Application Number:
JP22497390A
Publication Date:
April 09, 1992
Filing Date:
August 27, 1990
Export Citation:
Assignee:
IHARA CHEMICAL IND CO
International Classes:
C07C327/30; C07C319/02; C07C319/12; C07C323/34; (IPC1-7): C07C319/02; C07C319/12; C07C323/34; C07C327/30
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