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Patent Searching and Data


Title:
PRODUCTION OF ACYLOXYACETIC ACID COMPOUND
Document Type and Number:
Japanese Patent JPS6025954
Kind Code:
A
Abstract:

PURPOSE: To produce an acyloxyacetic acid compound useful as a synthetic intermediate of various agricultural chemicals and pharmaceuticals, especially an intermediate of herbicides, in high efficiency, without using a catalyst, by reacting an α-halogenoacetic acid compound with a carboxylic acid salt in a specific solvent.

CONSTITUTION: The objective compound of formula III is produced by reacting the α-halogenoacetic acid compound of formula I [X is Cl or Br; R1 and R2 are H or alkyl; R3 is OR' or NR"R'''(R' is alkyl; R" and R''' are H, alkyl or aryl)] with a carboxylic acid salt of formula II (R is H or alkyl; M is alkali metal or alkaline earth metal) in a solvent selected from dimethylsulfoxide, N,N-dimethylformamide, N,N-dimethylacetamide, hexamethylphosphoramide, acetonitrile and 1W3C lower alcohol, at 20W120°C. The amount of carboxylic acid salt can be reduced, and the formation of by-product caused by the polymerization of α- halogenoacetic acid can be suppressed.


Inventors:
YAMAMOTO TOSHIO
Application Number:
JP1983000133210
Publication Date:
February 08, 1985
Filing Date:
July 20, 1983
Export Citation:
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Assignee:
NIPPON SYNTHETIC CHEM IND
International Classes:
C07C69/675; C07C67/31; C07C67/313; (IPC1-7): C07C67/313; C07C69/675