Login| Sign Up| Help| Contact|

Patent Searching and Data


Title:
PRODUCTION OF ALKYLNITROGUANIDINE DERIVATIVES
Document Type and Number:
Japanese Patent JPH107645
Kind Code:
A
Abstract:

To selectively obtain a alkylnitroguanidine in one step useful for organic intermediates, medicines, agrochemicals, especially penetrative insecticides by alkylating nitroguanidine derivatives with an alkylating agent.

According to this method 2-nitroguanidine derivatives of formula II (R is an 1-4C alkyl) are capable of obtaining by alkylation of (A) nitroguanidine derivatives of formula I (A is a (substituted) heterocyclic ring or phenyl) in the presence of a base or an acid and base, in a solvent by an alkylating agent (preferably an 1-4C dialkylsulfuric acid). For example, 1- methyl-2-nitro-3-[(tetrahydro-3-franyl)methyl]guanidine is obtained by carrying out the reaction using 3-tetrahydrofurylmethylnitroguanidine as component A and dimethyl sulfuric acid as component B in the presence of sodium hydroxide, in dimethylformamide as solvent.


Inventors:
CHIBA YUTAKA
NAGAHARA KIYOTERU
MATSUNO YUUSEN
ODAKA KENJI
Application Number:
JP15814696A
Publication Date:
January 13, 1998
Filing Date:
June 19, 1996
Export Citation:
Click for automatic bibliography generation   Help
Assignee:
MITSUI PETROCHEMICAL IND
International Classes:
C07D213/36; A01N47/44; C07C277/08; C07C279/36; C07D213/61; (IPC1-7): C07C279/36; A01N47/44; C07C277/08; C07D213/36; C07D213/61