PURPOSE: To obtain a new aminodisaccharide comprising specific aminodisaccharides having oxazoline ring structure, capable of providing chitin or analogue polysaccharides by polyaddition reaction due to the action of chitinase and useful e.g. as a raw material for chitin or chitosan.
CONSTITUTION: This new aminodisaccharide comprises 2-methyl-{4-O-[2- acetamide-2-deoxy-β-glucopyranosyl]-l,2-dideoxy-α-glucopyrano} [2,1-d]-2- oxazoline expressed by formula I. The compound is reacted with chitinase in a buffer and subjected to polyaddition reaction due to enzyme catalyst to provide a chitin or its analogue polysaccharides. The aminodisaccharide is useful as a producing raw material for chitin or chitosan which has no problem on security of a raw material. The aminodisaccharide is obtained by reacting di-N-acetylchito-biosehexacetate with acetyl chloride in the presence of a base to chlorinate the acetate derivative and reacting the resultant chlorinated compound with acetonitrile in the presence of tetraethylammonium chloride, and further deprotecting hydroxyl group.
SHODA SHINICHIRO
KIYOSADA SHIYUNJI
KOBAYASHI SHIRO