Title:
PRODUCTION OF BETA-LACTAM COMPOUND
Document Type and Number:
Japanese Patent JPS63137696
Kind Code:
A
Abstract:
PURPOSE: To obtain the titled compound, having excellent antimicrobial action and inhibitory activity against β-lactamases and useful as medicines and veterinary drugs, by cultivating a specific microorganism belonging to the genus Streptomyces in a culture medium.
CONSTITUTION: A microorganism, e.g. Kitasatosporia papulosa AJ9458 (FERM P-9000), Streptomyces yumemiensis AJ9459 (FERM P-8999), etc., belonging to the genus Streptomyces or Kitasatosporia and having the ability to produce β-lactam compounds (salts) is cultivated in a culture medium, e.g. tyrosine agar culture medium, etc., preferably under aerobic condition at pH5W9 and 22W38°C to afford the aimed compound expressed by the formula.
Inventors:
NAKAMURA YOSHIHIRO
ISHII KOICHI
ONO EIJI
ISHIHARA MASARU
SHIBAI HIROSHIRO
ISHII KOICHI
ONO EIJI
ISHIHARA MASARU
SHIBAI HIROSHIRO
Application Number:
JP28277486A
Publication Date:
June 09, 1988
Filing Date:
November 27, 1986
Export Citation:
Assignee:
AJINOMOTO KK
International Classes:
C12P11/00; C12P37/00; C12R1/00; C12R1/465; (IPC1-7): C12P37/00; C12R1/00; C12R1/465