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Patent Searching and Data


Title:
PRODUCTION OF CHLORO-(AMINOMETHYL)PYRIDINES
Document Type and Number:
Japanese Patent JPH09176121
Kind Code:
A
Abstract:

To produce a compound useful as a synthetic raw material for pharmaceuticals, agrochemicals, etc., by using an easily handleable raw material easily available on an industrial scale.

A chloro-(aminomethyl)pyridine compound of the formula III [excluding 2-chloro-5-(aminomethyl)pyridine] is produced by reacting a chloro-(trichloromethyl) pyridine compound [excluding 2-chloro-5-(trichloromethyl) pyridine] with an amine of the formula II (R1 is H, an alkyl or an aminoalkyl; R2 is H or an alkyl) and hydrogen in the presence of a hydrogenation catalyst (e.g. Raney-nickel) under a hydrogen pressure between normal pressure to 100kg/cm2 at 0-100°C. The amounts of the compound of the formula II and the hydrogenation catalyst are 1-20 times mol and 1-20wt.% based on the compound of the formula I, respectively. The starting raw material of the formula I can be produced in one step by the chlorination of a methylpyridine compound.


Inventors:
AKEMASA HIROYUKI
UNO TOMOKO
Application Number:
JP35316195A
Publication Date:
July 08, 1997
Filing Date:
December 28, 1995
Export Citation:
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Assignee:
KOEI CHEMICAL CO
International Classes:
C07D213/61; B01J25/02; C07B61/00; (IPC1-7): C07D213/61; B01J25/02