PURPOSE: To obtain the titled substance economically, in improved selectivity of the cycloalkane conversion, by carrying out the liquid-phase oxidation of a cycloalkane compound with an O2-containing gas in the presence of a boron compound and in the copresence of formic acid or a formic acid salt.
CONSTITUTION: A cycloalkane compound (usually 3W12-membered compound, e.g. cyclopropane, methylcyclopentane, etc., especially preferably cyclohexane) is oxidized with an O2-containing gas in liquid phase in the presence of a boron compound. The above reaction is carried out by adding formic acid or a formic acid salt to the oxidation reaction system in an amount of preferably ≥10ppm, especially 200W5,000ppm in terms of formic acid based on the cycloalkane compound used as the raw material, usually at 100W250°C, especially at 150W180°C under an inert gas (e.g. N2) pressure of preferably about 5W25kg/cm2 G to obtain the titled compound.
HABU HARUO
HARADA SHIGEKI
WATANABE KOJI
DEJIMA EIJI