To provide a method for producing an ester simply efficiently in a high yield without enzyme deactivation.
In producing a carboxylic acid ester by reacting an alcohol with a carboxylic acid or its lower alkyl ester while circulation by using an apparatus equipped with a reactor and a circulation line for circulating a reaction solution, the reactor 2 for holding a catalyst containing an enzyme having esterification activity is maintained at 10-90°C a reaction solution flowing out from the reactor 2 is heated to a temperature ≥10°C higher than the reaction temperature and formed water or a formed lower alcohol are evaporated and removed. The reaction solution is controlled approximately at the reaction temperature and is returned to the reactor 2.
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| JP2023055465 | METHODS FOR PRODUCING STRIGOLACTONE BY CYANOBACTERIA AND YEAST |
| WO/2006/084643 | NOVEL GENE VCS 07 |
MAEDA TOSHIJI
MORISHITA MITSUGI
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