Title:
PRODUCTION OF INTERFERON
Document Type and Number:
Japanese Patent JPS6070098
Kind Code:
A
Abstract:
PURPOSE: Polyinosic acid and polycytidylic acid are heated and immobilized on a support to prepare an inducer that permits easy separation of interferon and the inducer is used to produce a large amount of interferons from lymphocytes and culture cells in high yield.
CONSTITUTION: An equimolar mixture of polyinosic acid and polycytidylic acid is heated at about 60W90°C for about 30W60min, then gradually cooled down to room temperature, then immobilized on a support to prepare an inducer. Then, the inducer is brought into contact with lymphocytes or culture cells suspended in a prescribed medium and they are kept at a specific temperature and the interferons formed are isolated.
Inventors:
SASAGAWA SHIGERU
TAMURA MOTOKO
ISHIKAWA YOSHIHIDE
TOKUNAGA EIICHI
TAMURA MOTOKO
ISHIKAWA YOSHIHIDE
TOKUNAGA EIICHI
Application Number:
JP17889183A
Publication Date:
April 20, 1985
Filing Date:
September 27, 1983
Export Citation:
Assignee:
NIHON SEKIJIYUUJISHIYA
International Classes:
C12P21/02; A61K38/21; A61P31/12; C12P21/00; C12R1/91; (IPC1-7): A61K45/02; C12P21/00; C12R1/91
Attorney, Agent or Firm:
Takehiko Suzue
Previous Patent: A recumbent form vigor determining device and the recumbent form vigor judging method
Next Patent: PRODUCTION OF GAMMA-INTERFERON
Next Patent: PRODUCTION OF GAMMA-INTERFERON