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Patent Searching and Data


Title:
PRODUCTION OF N-TERT-BUTOXYCARBAMATE
Document Type and Number:
Japanese Patent JPH08333326
Kind Code:
A
Abstract:

PURPOSE: To safely and simply produce an N-tert-butoxycarbamate useful as an intermediate for a synthetic raw substance for medicines under mild conditions in high yield without using an explosive substance by reacting an N-hydroxycarbamic acid ester with isobutene in the presence of an acidic catalyst.

CONSTITUTION: (A) A compound of the formula HO-NH-COOR [R is H or a group bonded through a carbon atom (e.g. a 1-15C alkyl, a 3-8C cycloalkyl, a 2-10C alkenyl, a 2-10C alkynyl, a 3-10C cycloalkenyl, a 6-14C aryl or a 7-16C aralkyl which may respectively be substituted with a lower alkoxy, a halogen, nitro or OH)] is reacted with (B) isobutene in the presence of (C) an acidic catalyst such as sulfuric acid to afford a compound of the formula (CH3)3 CO-NH-COOR.


Inventors:
Kawashima, Yasushi
Application Number:
JP1996000082272
Publication Date:
December 17, 1996
Filing Date:
April 04, 1996
Export Citation:
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Assignee:
TAKEDA CHEM IND LTD
International Classes:
B01J27/04; C07B61/00; C07C291/04; (IPC1-7): C07C291/04; B01J27/04
Attorney, Agent or Firm:
朝日奈 忠夫 (外2名)