PRODUCTION OF OPTICALLY ACTIVE DIAMINOHEXANONE DERIVATIVE

Title:

PRODUCTION OF OPTICALLY ACTIVE DIAMINOHEXANONE DERIVATIVE

Document Type and Number:

Japanese Patent JP3032110

Kind Code:

B2

Abstract:

PURPOSE: To obtain the compound suppressing HIV protease related to manifestation of proliferation and character of AIDS virus by hydrogenating a diamino- diphenyl-hexen-one derivative in the presence of a transition metal-containing catalyst.
CONSTITUTION: A (2S)-2,5-diamino-1,6-diphenyl-4-hexen-3-one derivative of the formula I [R1 is a (halogen-substituted) lower alkylcarbonyl, an arylcarbonyl or a lower alkoxycarbonyl; R2 and R3 each is an (alkoxy-substituted) aryll is hydrogenated in the presence of a transition metal-containing catalyst (preferably an activated metal such as ruthenium, rhodium, palladium or indium supported on a carrier selected from active carbon, silica, alumina or silica- alumina) to give the objective compound of the formula II.

More Like This:

JPH01289811	PREPARATION OF SILICON-CONTAINING POLYMER COMPOUND
JP4414225	Conversion of cyclopentadienylsilylamine to an organometallic complex containing a titanium bisalkoxy moiety or a titanium dichloride moiety
WO/2006/085531	CATALYST FOR PROPYLENE DIMERIZATION AND DIMERIZATION METHOD

Inventors:

山▲崎▼ 哲郎
Hidenori Unbayashi
Noboru Sayo
Toshiyuki Murayama
Noboru Sano
Ishizaki Kenro

Application Number:

JP4718294A

Publication Date:

April 10, 2000

Filing Date:

March 17, 1994

Export Citation:

Click for automatic bibliography generation Help

Assignee:

Takasago International Corporation

International Classes:

B01J31/22; B01J31/24; C07B61/00; C07C215/28; C07C221/00; C07C225/16; C07C231/12; C07C231/18; C07C233/36; C07C233/43; C07C233/78; C07C269/06; C07C271/20; (IPC1-7): C07C231/18; B01J31/22; B01J31/24; C07C233/36; C07C233/78; C07C269/06; C07C271/20

Other References:

Ｊ．Ｏｒｇ．Ｃｈｅｍ．，Ｖｏｌ．５８（１９９３）ｐ．１０２５−１０２９

Attorney, Agent or Firm:

Miyuki Ariga (3 outside)

Previous Patent: 帽子型滅菌ガーゼ

Next Patent: PACKAGING STRUCTURE OF DISPLAY DEVICE