Title:
PRODUCTION OF PENICILLIN AND DERIVATIVE THEREOF
Document Type and Number:
Japanese Patent JPS57105196
Kind Code:
A
Abstract:
A process for the preparation of a compound of formula (I): (I) wherein R1 is hydrogen, hydroxy, mercapto radical, a substituted or unsubstituted methoxy, ethoxy, methyl, ethyl, methyl thio, or ethylthio radical, a carbamoyloxy, carbamoylthio, C1-6 alkanoyloxy, C1-6 alkanoylthio, cyano, carboxy or carbamoyl radical; and R2 represents an acyl group which comprises hydrolysis of a compound of formula (II): (II) wherein R1 and R2 are as defined with respect to formula (I) hereinbefore and R3 represents benzyl or substituted benzyl; wherein the hydrolysis is catalyzed by a microbial serine proteinase.
Inventors:
IAN ROBAATO CHIESUTAA
ROOSON UIRIAMU PAUERU
DEBITSUDO GURIN ROBAATSU
ROOSON UIRIAMU PAUERU
DEBITSUDO GURIN ROBAATSU
Application Number:
JP17655981A
Publication Date:
June 30, 1982
Filing Date:
November 05, 1981
Export Citation:
Assignee:
BEECHAM GROUP LTD
International Classes:
C07D499/08; C12N11/08; C12N11/10; C12P37/00; (IPC1-7): C07D499/08; C12P37/00