Title:
PRODUCTION OF POLYKETIDES IN BACTERIA AND YEAST
Document Type and Number:
Japanese Patent JP2008022865
Kind Code:
A
Abstract:
To produce hybrid and novel polyketide synthases and polyketides.
Hybrid and novel polyketide synthases and polyketides are produced by use of a multiple vector system. The combinatorial possibilities offered by placing the various catalytic activities of PKS systems on separate vectors permits the construction of improved libraries of PKS and polyketides. In addition, polyketides can be produced in hosts that ordinarily do not produce polyketides by supplying, along with an expression system for the desired PKS, an expression system for holo ACP synthase.
Inventors:
BARR PHILIP J
SANTI DANIEL V
ASHLEY GARY W
ZIERMANN RAINER
SANTI DANIEL V
ASHLEY GARY W
ZIERMANN RAINER
Application Number:
JP2007269572A
Publication Date:
February 07, 2008
Filing Date:
October 16, 2007
Export Citation:
Assignee:
KOSAN BIOSCIENCES INC
International Classes:
C12N9/88; G01N33/50; C12N1/19; C12N1/21; C12N9/00; C12N9/10; C12N9/12; C12N15/09; C12N15/52; C12N15/70; C12N15/76; C12N15/81; C12P7/26; C12P7/42; C12P19/62; G01N33/15; C12R1/19; C12R1/865
Attorney, Agent or Firm:
Hidesaku Yamamoto
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