To provide a method for producing a saccharide containing sialic acid suitable for producing a large amount of the saccharide containing sialic acid at a low cost.
This method for producing a saccharide containing sialic acid is to transfer sialyl group from colominic acid to an acceptor saccharide such as lactose, by utilizing a transferring activity of a sialidase in a reaction vessel 1. While taking the produced saccharide containing sialic acid out of the reaction system by an ultra filtering membrane 3 quickly, the reaction is performed continuously by supplying a substrate. Since the produced sialyl lactose is quickly taken out from the reaction system, the utilization rate is kept as constant even on performing the continuous reaction, and the utilization rate of colominic acid is also kept as high.
KAWASE YUJI
MASUDA MINA