Title:
腎細胞癌の予後判定方法
Document Type and Number:
Japanese Patent JP6977933
Kind Code:
B2
Abstract:
It is intended to provide a rapid, convenient, and highly accurate method for determining the prognosis of cancer. The present invention provides a method for determining a tissue having renal cell carcinoma, comprising: (1) subjecting sample DNA to ion exchange chromatography, wherein the sample DNA is obtained by treating target genomic DNA prepared from a renal tissue of a subject with bisulfite, followed by PCR amplification; (2) calculating a derivative value of a detection signal of the chromatography; and (3) determining the renal tissue as being a tissue having renal cell carcinoma having poor prognosis when the derivative value calculated in the step (2) has two or more maximums.
Inventors:
Yaei Kanai
Kei Arai
Yuko Nemoto
Takuya Yotani
Kei Arai
Yuko Nemoto
Takuya Yotani
Application Number:
JP2017538132A
Publication Date:
December 08, 2021
Filing Date:
September 02, 2016
Export Citation:
Assignee:
National Cancer Research Center
Sekisui Medical Co., Ltd.
Sekisui Medical Co., Ltd.
International Classes:
C12Q1/686; C12N15/10; G01N33/50
Domestic Patent References:
| JP5897228B2 |
Foreign References:
| WO2014136930A1 | ||||
| WO2013035639A1 | ||||
| WO2014136539A1 | ||||
| WO2013168644A1 |
Other References:
Cancer Research,2015年08月01日,Vol.75, Suppl.15,p.1049
食品衛生学雑誌,1998年,Vol.39, No.6,p.426-430
Carcinogenesis,2012年,Vol.33, No.8,p.1487-1493
Analytical Biochemistry,2008年,Vol.375,p.354-360
Human Mutation,2002年,Vol.20,p.305-311
食品衛生学雑誌,1998年,Vol.39, No.6,p.426-430
Carcinogenesis,2012年,Vol.33, No.8,p.1487-1493
Analytical Biochemistry,2008年,Vol.375,p.354-360
Human Mutation,2002年,Vol.20,p.305-311
Attorney, Agent or Firm:
Alga Patent Office, a patent business corporation