Title:
増殖分化因子受容体、そのアゴニスト、およびアンタゴニスト、ならびにそれらの使用方法
Document Type and Number:
Japanese Patent JP5785525
Kind Code:
B2
Abstract:
The present invention provides an activin type IIB receptor (ActRIIB) for use in the treatment or prevention of a muscle disease or disorder in a mammal. The muscle disease or disorder may be muscular dystrophy, muscle atrophy or a muscle wasting disorder.
Inventors:
Lycein
Macferon Alexandra Sea.
Macferon Alexandra Sea.
Application Number:
JP2012147832A
Publication Date:
September 30, 2015
Filing Date:
June 29, 2012
Export Citation:
Assignee:
The Jones Hopkins University School of Medicine
International Classes:
A61K45/00; G01N33/50; A01K67/027; A61K31/7088; A61K38/22; A61K39/395; A61K48/00; A61P1/14; A61P3/00; A61P3/04; A61P3/06; A61P3/10; A61P21/00; A61P25/02; A61P43/00; C07K14/71; C07K14/715; C07K16/28; C07K16/42; C12N1/15; C12N1/19; C12N1/21; C12N5/10; C12N15/09; C12N15/85; G01N33/15; G01N33/53; G01N33/566; G01N33/74
Foreign References:
| WO2000043781A1 | ||||
| WO1998052038A1 |
Other References:
FEBS Lett.,1992年,Vol.312, No.1,pp.53-56
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Blood,1994年,Vol.83, No.8,p.2163-2170
J. Biol. Chem.,1998年,Vol.273, No.40,p.25628-25636
Mol. Cell Biol.,1996年,Vol.14, No.6,p.3810-3821
Mol. Cell Biol.,1996年,Vol.16, No.3,p.1066-1073
GENES & DEVELOPMENT,1997年,Vol.11,p.1812-1826
Dev Growth Differ.,1999年,Vol.41, No.2,pp.119-133
Attorney, Agent or Firm:
Hatsushi Shimizu