Title:
プロリルヒドロキシラーゼ阻害剤
Document Type and Number:
Japanese Patent JP2011525924
Kind Code:
A
Abstract:
The invention described herein relates to certain pyrimidinedione N-substituted glycine derivatives of formula (I) which are antagonists of HIF prolyl hydroxylases and are useful for treating diseases benefiting from the inhibition of this enzyme, anemia being one example.
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Inventors:
James, A. Brackley, The, Third
Antony, nicholas, show
Losanna, Tedesco
Yonghui, Wan
Kenneth, Jay Wiggal
You, Hongui
Antony, nicholas, show
Losanna, Tedesco
Yonghui, Wan
Kenneth, Jay Wiggal
You, Hongui
Application Number:
JP2011516502A
Publication Date:
September 29, 2011
Filing Date:
June 23, 2009
Export Citation:
Assignee:
GlaxoSmithKline LLC
International Classes:
C07D213/22; A61K31/4412; A61K31/4709; A61K31/4725; A61K31/497; A61K31/5377; A61P7/06; A61P43/00; C07D213/82; C07D401/06; C07D401/12; C07D405/12; C07D409/06; C07D417/12
Attorney, Agent or Firm:
Hirohito Katsunuma
Yukitaka Nakamura
Noritaka Yokota
Takeyasu Ito
Hiroyuki Fujii
Yukitaka Nakamura
Noritaka Yokota
Takeyasu Ito
Hiroyuki Fujii