Title:
PROPANOL AMINE DERIVATIVE
Document Type and Number:
Japanese Patent JPS5748948
Kind Code:
A
Abstract:
Propanolamine derivatives of the formula: wherein R2 is CH3SO or CH3SO2; R3 is hydrogen, methyl or methoxy; or R2 and R3 are together -S(O)m(CH2)4-when S is attached at R2 or -(CH2)nS(O)m- when S is attached at R3(where m=1 or 2 and n=3 or 4); R4 is hydrogen or alkyl C1-4; Z is -(CH2)2- or and their non-toxic salts. Processes for the preparation and pharmaceutical compositions thereof. The compounds exhibit both beta -adrenoreceptor antagonist activity and vasodilator activity and are indicated for use in the treatment of hypertension.
Inventors:
ANDORIYUU JIYON GIRUBII BAKUSU
MARUKAMU MEIYAAZU
MARUKAMU MEIYAAZU
Application Number:
JP10683781A
Publication Date:
March 20, 1982
Filing Date:
July 08, 1981
Export Citation:
Assignee:
RECKITT & COLMANN PROD LTD
International Classes:
A61K31/38; A61P9/08; C07C67/00; C07C213/00; A61K31/135; C07C217/30; C07C313/00; C07C315/04; C07C317/22; C07D335/06; C07D337/06; C07D337/08; (IPC1-7): A61K31/135; C07C93/06; C07C147/10; C07D337/06
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